Hot Sell Small Molecular API Amuvatinib (CAS: 850879-09-3)

Model NO.: 850879-09-3
Product Name: Amuvatinib
CAS No.: 850879-09-3
Mf: C23h21n5o3s
MW: 447.51
Delivery by: DHL, TNT, FedEx, Hkems, UPS, etc
Export Markets: Global
Trademark: NEWBIO
Transport Package: Aluminum Foil Bags
Specification: SGS
Origin: China
HS Code: 0000000000
Model NO.: 850879-09-3
Product Name: Amuvatinib
CAS No.: 850879-09-3
Mf: C23h21n5o3s
MW: 447.51
Delivery by: DHL, TNT, FedEx, Hkems, UPS, etc
Export Markets: Global
Trademark: NEWBIO
Transport Package: Aluminum Foil Bags
Specification: SGS
Origin: China
HS Code: 0000000000
Chemical Information:
 
Product Name
Amuvatinib
Molecular Formula C23H21N5O3S
Molecular Weight 447.51
Storage Store at -20°C 
Targets c-KitD816H
IC50 10 nM
Dosage
10 mg / kg-75mg / kg (i.p.) or 50 mg / kg-200 mg / kg
 
Stability
3 years   - 20 ºC powder
6 months  -80 ºC dissolved in a solvent
Solubility Soluble in DMSO > 10 mM
General tips For obtaining a higher solubility , please warm the tube at 37 ºC and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20ºC for several months.
Shipping Condition
Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request


Details:
 
Synonyms:N-(1,3-Benzodioxol-5-ylmethyl)-4-benzofuro[3,2-d]pyrimidin-4-yl-1-piperazinecarbothioamide;1-Piperazinecarbothioamide, N-(1,3-benzodioxol-5-ylmethyl)-4-benzofuro(3,2-D)pyrimidin-4-yl-;Mp470;AMuvatinib;HPK 56;MP-470(MP 470);AMuvatinib (MP-470);AMuvatinib (MP-470, HPK 56)
   
Description:Amuvatinib (MP-470) is a potent and multi-targeted inhibitor of c-Kit, PDGFRα and Flt3 with IC50 of 10 nM, 40 nM and 81 nM, respectively.
 
 
Application:
MP-470 acts on LNCaP and PC-3, DU145 cells instead, toxic, IC50 4 μM, respectively and 8 μM, and 10 μM in at a little proliferation. MP-470 (10 μM) effect on LNCaP cells, the cell cycle arrest in G1 and reduced Akt and ERK1 / 2 phosphorylation. [4] MP-470 (10 μM) acting on the SF767 cells, inhibition of c-Met phosphorylation, and the cells sensitive to radiation. MP-470 (10 μM) and radiation combined treatment, inhibiting GSK-3β activity, induction of apoptosis, and possibly by inhibiting the destruction of dsDNA b Rad51 fracture repair. [5,6]
 
 
Notification:This compound is used only for research and not for human trials!


Other Small Molecular API:
 
AZD9291 1421373-65-0
E7080 417716-92-8
Afatinib diMaleate 439081-18-2
XL184 S-MALATE 1140909-48-3
Crizotinib 877399-52-5
Axitinib 319460-85-0
WZ4002 1213269-23-8
Vandetanib 443913-73-3
Sunitinib 557795-19-4
Regorafenib 755037-03-7
Imatinib 152459-95-5
Foretinib 849217-64-7
trametinib 871700-17-3
Tivozanib 475108-18-0
Pelitinib  257933-82-7
Cediranib 288383-20-0
Selumetinib 606143-52-6
Tozasertib 639089-54-6
CapMatinib 1029712-80-8
Amuvatinib 850879-09-3
Lestaurtinib 111358-88-4
Brivanib 649735-46-6



 
1.The parcels will be sent within 24 hours once the order is verified.
2.Packaging is fully in accordance with customer demand.
3.There will be discounts whether you are an old customer or not.

To your satisfiction, here are our advantages

1.High quality and competetive price
1)we can offer coa certificate and official invoice.
2)we are manufacturer with own lab and factory, can provide high quality products with factory price.
3)products purity is test by our quality department strictly before sending, and you can also ask the third testing organization come and inspect, such as (sgs/ cti/ its), only after your confirmation will we send it out to you.

2.Fast and safe delivery
1)products can be sent out in 24 hours after payment.Tracking number available, fixed service person are 7x24h for you to contact.
2) secure and discreet shipment.Various transportation methods for your choice, like dhl/ups/tnt/fedex/sf-express.
3)customs pass and satisfied rate >99%.
4)for hot sale products we have stock in there for transferring.

3 we have clients throughout the world
1) professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
2) market feedback and goods feedback will be appreciated, meeting customers' requirement is our responsibility.
3) high quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers. 



Delivery:
1) Products can be sent out within 24 hours after payment. 
2) Secure and discreet shipment. 
3) Various methods for your choice, like DHL/TNT/FedEx/SF-express.

Commitment:
1. We are manufacturer with own factory and we sale this product at a best quality and low price.
2. This product is available in stock, please contact the sale for more details.
3. We have QA & QC department to guarantees the ex-factory product pass rate can reach 100%. 


====================================================
Contactct:
Telephone: +86-027-87002705
Mobile: +86-13638641831 +86-13277093700
 
 
FaceBook: https://www.facebook.com/newbiopharma/
Website:  http://www.newbiopharm.com/
Online Store: http://biocar.en.made-in-china.com/
©Wuhan Newbio Pharm-Tech Co., Ltd.


Newbio is a reliable supplier and looks for a long term business relationship!!!
Chemical Information:
 
Product Name
Amuvatinib
Molecular Formula C23H21N5O3S
Molecular Weight 447.51
Storage Store at -20°C 
Targets c-KitD816H
IC50 10 nM
Dosage
10 mg / kg-75mg / kg (i.p.) or 50 mg / kg-200 mg / kg
 
Stability
3 years   - 20 ºC powder
6 months  -80 ºC dissolved in a solvent
Solubility Soluble in DMSO > 10 mM
General tips For obtaining a higher solubility , please warm the tube at 37 ºC and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20ºC for several months.
Shipping Condition
Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request


Details:
 
Synonyms:N-(1,3-Benzodioxol-5-ylmethyl)-4-benzofuro[3,2-d]pyrimidin-4-yl-1-piperazinecarbothioamide;1-Piperazinecarbothioamide, N-(1,3-benzodioxol-5-ylmethyl)-4-benzofuro(3,2-D)pyrimidin-4-yl-;Mp470;AMuvatinib;HPK 56;MP-470(MP 470);AMuvatinib (MP-470);AMuvatinib (MP-470, HPK 56)
   
Description:Amuvatinib (MP-470) is a potent and multi-targeted inhibitor of c-Kit, PDGFRα and Flt3 with IC50 of 10 nM, 40 nM and 81 nM, respectively.
 
 
Application:
MP-470 acts on LNCaP and PC-3, DU145 cells instead, toxic, IC50 4 μM, respectively and 8 μM, and 10 μM in at a little proliferation. MP-470 (10 μM) effect on LNCaP cells, the cell cycle arrest in G1 and reduced Akt and ERK1 / 2 phosphorylation. [4] MP-470 (10 μM) acting on the SF767 cells, inhibition of c-Met phosphorylation, and the cells sensitive to radiation. MP-470 (10 μM) and radiation combined treatment, inhibiting GSK-3β activity, induction of apoptosis, and possibly by inhibiting the destruction of dsDNA b Rad51 fracture repair. [5,6]
 
 
Notification:This compound is used only for research and not for human trials!


Other Small Molecular API:
 
AZD9291 1421373-65-0
E7080 417716-92-8
Afatinib diMaleate 439081-18-2
XL184 S-MALATE 1140909-48-3
Crizotinib 877399-52-5
Axitinib 319460-85-0
WZ4002 1213269-23-8
Vandetanib 443913-73-3
Sunitinib 557795-19-4
Regorafenib 755037-03-7
Imatinib 152459-95-5
Foretinib 849217-64-7
trametinib 871700-17-3
Tivozanib 475108-18-0
Pelitinib  257933-82-7
Cediranib 288383-20-0
Selumetinib 606143-52-6
Tozasertib 639089-54-6
CapMatinib 1029712-80-8
Amuvatinib 850879-09-3
Lestaurtinib 111358-88-4
Brivanib 649735-46-6



 
1.The parcels will be sent within 24 hours once the order is verified.
2.Packaging is fully in accordance with customer demand.
3.There will be discounts whether you are an old customer or not.

To your satisfiction, here are our advantages

1.High quality and competetive price
1)we can offer coa certificate and official invoice.
2)we are manufacturer with own lab and factory, can provide high quality products with factory price.
3)products purity is test by our quality department strictly before sending, and you can also ask the third testing organization come and inspect, such as (sgs/ cti/ its), only after your confirmation will we send it out to you.

2.Fast and safe delivery
1)products can be sent out in 24 hours after payment.Tracking number available, fixed service person are 7x24h for you to contact.
2) secure and discreet shipment.Various transportation methods for your choice, like dhl/ups/tnt/fedex/sf-express.
3)customs pass and satisfied rate >99%.
4)for hot sale products we have stock in there for transferring.

3 we have clients throughout the world
1) professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
2) market feedback and goods feedback will be appreciated, meeting customers' requirement is our responsibility.
3) high quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers. 



Delivery:
1) Products can be sent out within 24 hours after payment. 
2) Secure and discreet shipment. 
3) Various methods for your choice, like DHL/TNT/FedEx/SF-express.

Commitment:
1. We are manufacturer with own factory and we sale this product at a best quality and low price.
2. This product is available in stock, please contact the sale for more details.
3. We have QA & QC department to guarantees the ex-factory product pass rate can reach 100%. 


====================================================
Contactct:
Telephone: +86-027-87002705
Mobile: +86-13638641831 +86-13277093700
 
 
FaceBook: https://www.facebook.com/newbiopharma/
Website:  http://www.newbiopharm.com/
Online Store: http://biocar.en.made-in-china.com/
©Wuhan Newbio Pharm-Tech Co., Ltd.


Newbio is a reliable supplier and looks for a long term business relationship!!!

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