Relationship between intestinal bacteria, antibiotics and the onset of type 1 diabetes

Relationship between intestinal bacteria, antibiotics and the onset of type 1 diabetes

August 25, 2016 Source: Noble

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More than 30 million people in the United States are diagnosed with diabetes.

About 5% of these diabetics are classified as type 1 diabetes.

Type 1 diabetes, which is usually diagnosed among young adults and children, is an autoimmune disease sometimes referred to as juvenile diabetes.

The individual's immune system attacks and destroys specific cells in the pancreas—the insulin-producing islet cells.

As insulin continues to decrease, blood sugar balance changes and damages nerves and blood vessels.

The exact cause of type 1 diabetes is unclear, and both genetic and environmental factors are considered.

The number of people diagnosed with type 1 diabetes is increasing for unknown reasons. According to some estimates, patients with type 1 diabetes worldwide increase by 3% annually.

The rise of antibiotics

The theory of the interaction between antibiotics and intestinal bacteria can be used to explain the increase in type 1 diabetes. The microbes that inhabit our gut – the gut flora or “healthy” bacteria – have evolved with humans and are now closely linked to the normal functioning of our bodily functions.

Incredibly, there are many more bacteria in our bodies than in our bodies.

It has been suggested that intestinal biomes have other effects, such as helping to develop the developing immune system but not sensitive. In other words, we are able to safely access a variety of microorganisms as we grow up, and the immune system is less likely to be triggered.

In recent years, children's exposure to microbes that destroy microorganisms has steadily increased. When American children reach the age of 10, they receive an average of 10 courses of antibiotic treatment.

“This is the first study on the use of antibiotics to alter the gut flora and have a lasting impact on immune and metabolic development, ultimately leading to autoimmune diseases.

We are eager to see that these findings can influence the discovery of future treatments for type 1 diabetes and further research in the field of vaccines. Jessica Dunne, research director of the Juvenile Diabetes Research Foundation, said

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