A "bad news"! "Shen medicine" aspirin increases cancer risk May 7, 2018 Source: Biological Exploration of: Chen Aspirin is one of the three classic drugs in the history of medicine. A large number of previous studies have shown that this "medicine" is expected to "extend the battle" in the field of anti-cancer. However, a recent paper published a "bad news": aspirin increases the risk of men suffering from melanoma... Image source: Journal of the American Academy of Dermatology (DOI: https://doi.org/10.1016/j.jaad.2018.03.031) Published in the Journal of the American Academy of Dermatology, entitled "Malignant melanoma associated with chronic once daily aspirin exposure in males: a large, single-center, urban, US patient population cohort study from the Research on Adverse Drug events And Reports In the (RADAR) project, a team of scientists from Northwestern University's Feinberg School of Medicine confirmed that men who took aspirin once a day were almost twice as likely to have melanoma as men who did not take aspirin daily. 1, amazing discovery Specifically, the study collected medical record data consisting of 195,140 patients (aged between 18 and 89 years of age with no history of melanoma) for at least 5 years. Among them, 1,187 patients belonged to the “aspirin-exposed group†(aspirin-exposed from January 2005 to December 2006, at least one year of aspirin, once daily, at a dose of 81 or 325 mg), and the rest belonged to "Untreated aspirin-unexposed" (control group). Follow-up results showed that 26 people (including men and women) were diagnosed with melanoma during the survey, accounting for 2.19% of the total number; in the control group, 1,676 people (including men and women) were surveyed. During the period, melanoma was diagnosed, accounting for 0.86% of the total. After classifying participants by gender, the scientists found that “men who took aspirin†were nearly twice as likely to be diagnosed with melanoma as “men who did not take aspirinâ€. The researchers were surprised by the results because aspirin was previously reported to reduce the risk of stomach, colon, prostate and breast cancer. Image source: Network Dr. Beatrice Nardone, who led the study, speculated that one reason men might be more vulnerable to “harm†might be that they expressed fewer protective enzymes than women, such as superoxide dismutase, catalase. . A lower level of protective enzymes means that men have a higher level of oxidative cell damage, which in turn may lead to melanoma. 2. Research significance According to a 2005 study, nearly half of people aged 65 or older took aspirin daily or every other day. In a national survey of adults in the United States in 2015, about half said they used aspirin regularly. Dr. Nardone said: “Considering the widespread use of aspirin and the potential clinical implications associated with melanoma, patients and healthcare providers need to be aware that this drug has the potential to increase the risk of men suffering from melanoma. However, this does not mean Men should stop taking aspirin for reducing the risk of heart attack." Based on their findings, Dr. Nardone advises relevant personnel to increase patient education about sun exposure, avoid using tanning beds, and undergo dermatologists' examinations, especially for those who are already suffering from skin. A person at high risk of cancer. References: 1) Daily aspirin linked to higher risk in men Isolation Gowns,Blue Isolation Gowns,Hospital Isolation Gowns,Disposable Isolation Gowns Henan Anbang Medical Supplies Co., Ltd. , https://www.anbangmedical.com
