Universal A.I. Sheaths With Blue Insert Blue Insert Universal A.I. Sheaths,Universal Sheaths,Sheath Blue Insert Split-Non,Endoscope Hydrophilic Coating Dilators Jinan Mucho Commercial Inc. , https://www.muchovet.com
Functions :
AICAR (AICA-Riboside) strongly inhibits the transcription of PPAR&alpha and the coactivation of PPAR&alpha. In adipocyte studies it has been shown to antagonize lipolysis induced by isoprenaline and has been suggested for use in kinase cascade research. Additionally, research indicates that AICAR blocks the differentiation of 3T3-L1 (sc-2243) adipocytes. Studies demonstrate that AICAR can mimic the activity of insulin (sc-211647) by activating AMPK (AMP-activated protein kinase), and affecting the expression of PEPCK-M (PEPCK) and glucose-6-phosphatase (G6Pase). The 5-aminoimidazole-4-carboxamide ribonucleoside (ZMP) is the monophosphorylated derivative of AICA-Riboside, and it can serve as the substrate for the aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC). AICAR is an inhibitor of Hsp90, mTOR and p70 S6 Kinase.
AMP-activated protein kinase (AMPK) functions as a metabolic sensor that regulates lipid and glucose metabolism to maintain cellular energy homeostasis and to protect against metabolic stress.AICAR is a selective activator of AMPK in both hepatocytes and adipocytes. At 0.5 mM it inhibits the synthesis of fatty acids and sterols and inactivates HMG-CoA reductase in rat hepatocytes.AICAR (0.5 mM) inhibits insulin-stimulated glucose uptake to 62% of controls and reduces GLUT4 translocation 2.5-fold in 3T3-L1 adipocytes. It also blocks the expression of pro-inflammatory cytokines (TNF-α/IL-1β and IL-6), iNOS, COX-2, and MnSOD genes in glial cells and macrophages by inhibiting NFκB and C/EBP pathways.
COA of MK-2866 :
Â
Item
Specification
Result
 Appearance
An odorless, almost white or white powder
pass
 Identificaton
The retention time of the major peak isÂ
confirm to the RSpass
 Loss on Drying
Not more than 0.5%
0.33%
Assay(HPLC)
Not less than 99.0%
99.59%
Ignition residue
Not more than 0.1%
pass
Heavy metal
Not more than 20 ppm
pass
Mk-2866Â Function :
1.Enobosarm (Ostarine, MK-2866, GTx-024) - affects both muscle and bone, intended mainly for osteoporosis but also general treatment for andropause and reversing muscle sarcopenia in the elderly and for cachexia in cancer patients .
2.Nonsteroidal selective androgen receptor modulator (SARM) used in the treatment of osteoporosis and muscle wasting in animal models. A potential compound for the treatment of hypoactive sexual desire disorder .
Our Advantages :
1.High quality
SHU OU is a manufacturer with its own lab and factory.Â
The purity of our product  is tested by our quality department before it is shipped to our clients.Â
As our client, you can also request for a third party evaluator such as SGS, CTI or ITS,Â
when you confirm your order and before it is shipped.Â
Â
2. Competitive Price
SHU OU does not only supply products but we also manufacture goods to ensure our client satisfaction.
We deal directly with our clients therefore we provide you with the best price on the market.
Â
3. Safe and Rapid Delivery
SHU OU works with professional shipping companies to ensure fast and efficient delivery.Â
As experts in our field we have a lot of experience in dealing with all kinds of foreign clients.Â
We know the best way to ship products to the U.S, EU, Australia, Canada, South America and other regions of the world.Â
Products can be sent out within 24 hours after payment.Â
A tracking number will be made available after products have been shipped.Â
We also provide a 24 hours, 7 days a week customer service, ready to take your queries.Â
Â
4. Quick Response
SHU OU ensures that all our client enquiries are addressed as quickly as they are received. Â
We can contacted through email,Skype, Facebook, and twitter.
All your enquiries will receive response within the day.
Â
SARM
CAS.NO.
Ostarine / MK-2866
841205-47-8
Andarine S4 / GTX-007
401900-40-1
GW-501516Â /Â Cardarine
317318-70-0
LGD-4033Â /Â Ligandrol
1165910-22-4
MK-677Â /Â Ibutamoren
159752-10-0
SR9009/SR9011
1379686-30-2
RAD140
118237-47-0
YK11
431579-34-9
Packaging & Delivery Process
1. With sufficient stock, so we can deliver promptly at the very day upon receipt of the payment.
2. Sophisticated and professional logistic agent. We take responsibility to provide our customers with fast delivery and secure shipping.
3. Well-trained and disciplined packing team. Unique ways to ship 10 grams to 100kg powders at one time to your destination. Fast and discreet shipment could be arranged for customs to pass The Guaranteed.Â
4. Packing pictures and tacking code are provided within 12 hours after receiving the payment. Updated tracking information will be provided every other day.
5. After-sale service: Any questions or problems after receiving the product, please feel free to contact us. Problems would be solved for you immediately.
China Legit Lab Pharmaceutical Sarms Enobosarm Mk-2866 Ostarine
Functions :
AICAR (AICA-Riboside) strongly inhibits the transcription of PPAR&alpha and the coactivation of PPAR&alpha. In adipocyte studies it has been shown to antagonize lipolysis induced by isoprenaline and has been suggested for use in kinase cascade research. Additionally, research indicates that AICAR blocks the differentiation of 3T3-L1 (sc-2243) adipocytes. Studies demonstrate that AICAR can mimic the activity of insulin (sc-211647) by activating AMPK (AMP-activated protein kinase), and affecting the expression of PEPCK-M (PEPCK) and glucose-6-phosphatase (G6Pase). The 5-aminoimidazole-4-carboxamide ribonucleoside (ZMP) is the monophosphorylated derivative of AICA-Riboside, and it can serve as the substrate for the aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC). AICAR is an inhibitor of Hsp90, mTOR and p70 S6 Kinase.
AMP-activated protein kinase (AMPK) functions as a metabolic sensor that regulates lipid and glucose metabolism to maintain cellular energy homeostasis and to protect against metabolic stress.AICAR is a selective activator of AMPK in both hepatocytes and adipocytes. At 0.5 mM it inhibits the synthesis of fatty acids and sterols and inactivates HMG-CoA reductase in rat hepatocytes.AICAR (0.5 mM) inhibits insulin-stimulated glucose uptake to 62% of controls and reduces GLUT4 translocation 2.5-fold in 3T3-L1 adipocytes. It also blocks the expression of pro-inflammatory cytokines (TNF-α/IL-1β and IL-6), iNOS, COX-2, and MnSOD genes in glial cells and macrophages by inhibiting NFκB and C/EBP pathways.
COA of MK-2866 :
Â
Item
Specification
Result
 Appearance
An odorless, almost white or white powder
pass
 Identificaton
The retention time of the major peak isÂ
confirm to the RSpass
 Loss on Drying
Not more than 0.5%
0.33%
Assay(HPLC)
Not less than 99.0%
99.59%
Ignition residue
Not more than 0.1%
pass
Heavy metal
Not more than 20 ppm
pass
Mk-2866Â Function :
1.Enobosarm (Ostarine, MK-2866, GTx-024) - affects both muscle and bone, intended mainly for osteoporosis but also general treatment for andropause and reversing muscle sarcopenia in the elderly and for cachexia in cancer patients .
2.Nonsteroidal selective androgen receptor modulator (SARM) used in the treatment of osteoporosis and muscle wasting in animal models. A potential compound for the treatment of hypoactive sexual desire disorder .
Our Advantages :
1.High quality
SHU OU is a manufacturer with its own lab and factory.Â
The purity of our product  is tested by our quality department before it is shipped to our clients.Â
As our client, you can also request for a third party evaluator such as SGS, CTI or ITS,Â
when you confirm your order and before it is shipped.Â
Â
2. Competitive Price
SHU OU does not only supply products but we also manufacture goods to ensure our client satisfaction.
We deal directly with our clients therefore we provide you with the best price on the market.
Â
3. Safe and Rapid Delivery
SHU OU works with professional shipping companies to ensure fast and efficient delivery.Â
As experts in our field we have a lot of experience in dealing with all kinds of foreign clients.Â
We know the best way to ship products to the U.S, EU, Australia, Canada, South America and other regions of the world.Â
Products can be sent out within 24 hours after payment.Â
A tracking number will be made available after products have been shipped.Â
We also provide a 24 hours, 7 days a week customer service, ready to take your queries.Â
Â
4. Quick Response
SHU OU ensures that all our client enquiries are addressed as quickly as they are received. Â
We can contacted through email,Skype, Facebook, and twitter.
All your enquiries will receive response within the day.
Â
SARM
CAS.NO.
Ostarine / MK-2866
841205-47-8
Andarine S4 / GTX-007
401900-40-1
GW-501516Â /Â Cardarine
317318-70-0
LGD-4033Â /Â Ligandrol
1165910-22-4
MK-677Â /Â Ibutamoren
159752-10-0
SR9009/SR9011
1379686-30-2
RAD140
118237-47-0
YK11
431579-34-9
Packaging & Delivery Process
1. With sufficient stock, so we can deliver promptly at the very day upon receipt of the payment.
2. Sophisticated and professional logistic agent. We take responsibility to provide our customers with fast delivery and secure shipping.
3. Well-trained and disciplined packing team. Unique ways to ship 10 grams to 100kg powders at one time to your destination. Fast and discreet shipment could be arranged for customs to pass The Guaranteed.Â
4. Packing pictures and tacking code are provided within 12 hours after receiving the payment. Updated tracking information will be provided every other day.
5. After-sale service: Any questions or problems after receiving the product, please feel free to contact us. Problems would be solved for you immediately.
China Legit Lab Pharmaceutical Sarms Enobosarm Mk-2866 Ostarine
Model NO.: 841205-47-8
CAS: 841205-47-8
Appearance: White Crystalloid Powder
Express Way: EMS, FedEx, TNT, DHL, Hkems
Alias: Mk-2866
Trademark: WHSO
Transport Package: Foil Bag
Specification: 99%
Origin: Hongkong
HS Code: 121425246
Model NO.: 841205-47-8
CAS: 841205-47-8
Appearance: White Crystalloid Powder
Express Way: EMS, FedEx, TNT, DHL, Hkems
Alias: Mk-2866
Trademark: WHSO
Transport Package: Foil Bag
Specification: 99%
Origin: Hongkong
HS Code: 121425246
China Legit Lab Pharmaceutical Sarms Enobosarm Mk-2866 Ostarine