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Scientists developed a diaphragm-wrapped "nano-robot" to detoxify blood
The medical network donated human blood on June 6th - even the blood in our body infected with bacteria is not a good thing. However, scientists at the University of California, San Diego are developing a micro-ultrasonic powered robot to remove bacteria from the blood. The basic "nanobot" was created by a team led by Professor Joseph Wang and consists of the microscopic length of the gold nanowires. With external application of ultrasound, liquids, including blood, can push them to mix thoroughly with them.
During the development of Liangfang Zhang and colleagues, these nano-robots were wrapped in a membrane composed of platelets and erythrocyte membranes. The coating was prepared by first separating the membranes from their respective cells, fusing two different types of membranes together using high frequency sound waves, and then applying them to the gold nanowires by chemical processes.
The resulting robot is approximately one-fifth the width of a human hair and can pass through the blood at a rate of 35 microns per second when subjected to ultrasound. When they do so, pathogens such as MRSA (methicillin-resistant Staphylococcus aureus) bind to surface proteins in the platelet membrane, and toxins produced by these bacteria are neutralized by the red blood cell membrane.
In laboratory testing, nanobots are used to treat blood samples contaminated with MRSA. Within five minutes, only one-third of the bacteria and toxins remained in the treated samples. Now scientists plan to test live animals.
"By integrating natural cell coatings onto synthetic nanomachines, we can give new functions to small robots, such as removing pathogens and toxins from the body and other matrices," the scientists said. “This is a proof-of-concept platform for a variety of therapeutic and biodetoxification applications.â€
Scientists recently published a paper on the study in the journal Science Robotics.