Injection test of injection liquid

The needle-through nature of injectable solutions is a very important indicator for intravenous and subcutaneous injections. The definition of the needle is as follows: the injection liquid can be smoothly taken out through the injection syringe and the injection needle, and the needle wall is not blocked. By testing the needle-to-needle performance of the injection, the manufacturer can optimize the usability and patient comfort while ensuring quality control and product safety.

The needle-through nature of the injectable solution is primarily the force required to push the solution out of the injection needle by the syringe. Universal TA texture analyzer is widely used in the pharmaceutical industry. It can test tablets, pills, capsules, ointments, suppositories, film sponges, sprays, medical excipients, absorbents, thinners, adhesives, syrups, lactose, medical tapes. , injection needles, syringes, bandages, membrane materials, bone substitute materials, medical packaging materials, etc. In terms of the test solution, we have designed a special needle test device.

Fixing the syringe on the syringe support device, applying pressure to the syringe piston through the upper fixture connected to the force sensing element, pushing the injection solution through the syringe and the needle until the solution is pushed out of the needle, and calculating the average force of the solution flowing out of the needle as a solution Needle test indicators.

The needle penetration of the test solution is susceptible to the syringe plunger diameter, injection flow rate, needle diameter and length, and viscosity of the injection solution. The viscosity of the injection is related to the needle-forming property and stability of the preparation. The viscosity is too small, the particles are easy to coagulate, and the system tends to be unstable. If the viscosity is too large, the needle is not good and the injection is inconvenient.

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