Release date: 2015-12-29
Huang Rongqin of Fudan University School of Pharmacy constructed a fluorescence sensor based on mesoporous carbon sphere for multiplex diagnosis of tumors in vivo and in vitro. The sensor specifically recognizes tumor markers by mesoporous carbon spheres (OMCN) and fluorescent dyes (Cy3). Non-covalent π-π interaction of the short nucleotide sequence (P0) of the material (MUC1), achieving fluorescence quenching and recovery of the MUC1-specific response. Based on this, the sensor can not only detect the concentration of the tumor marker MUC1 in the liquid, but also exhibit a wide linear range (0.1-10.6 μmol/L), a low detection limit (6.52 nmol/L) and good selectivity; The sensor also specifically detects the concentration of cancer cells in the liquid, with a linear range (104-2 × 106 cells / mL) and a detection limit (8500 cells / mL). More importantly, the fluorescence sensor is capable of sensitive and specific imaging of tumor cells, tumor tissues, ex vivo tumors, and tumors in vivo. Therefore, the successful construction of this sensor provides a powerful technology platform for multiple diagnosis of cancer.
Http://pubs.acs.org/doi/abs/10.1021/acsnano.5b05137 Source: X-MOL
Fluorine-Containing Benzoic Acid
The Fluorine-Containing Benzoic Acid series is very common form of the fluorochemical compounds, it has many product types and derivatives. Most of products are in white crystalline powder, some of products are Colorless monoclinic prismatic crystals. It was widely used as fungicide intermediates, also used in the etching process. The Fluorine-Containing Benzoic Acid series are mostly in high value-added , less polluting products. We are trying our best to make our production dock with market to give accurate and effective services for the market .
Containing Benzoic Acid,2,3-Difluorobenzoic Acid,Methoxybenzoic Acid
Taizhou Volsen Chemical Co., Ltd. , https://www.volsenchem.com