Quantum dot microchips improve the efficiency of cancer therapy

Quantum dot microchips improve the efficiency of cancer therapy

October 23, 2018 Source: Science and Technology Daily

Window._bd_share_config={ "common":{ "bdSnsKey":{ },"bdText":"","bdMini":"2","bdMiniList":false,"bdPic":"","bdStyle":" 0","bdSize":"16"},"share":{ }};with(document)0[(getElementsByTagName('head')[0]||body).appendChild(createElement('script')) .src='http://bdimg.share.baidu.com/static/api/js/share.js?v=89860593.js?cdnversion='+~(-new Date()/36e5)];

The Moscow Institute of Engineering Physics at the National Institute of Nuclear Energy Research in Russia collaborates with researchers at the University of Nantes and the University of Reims in Champagne-Ardenne, France, to develop a microchip based on quantum dots to help discover high-efficiency kinase inhibitors ( A substance that reduces activity), which is expected to increase the efficiency of anticancer therapy many times. The results of the study were published in the Science Report.

"I have developed a chip with quantum dots as a response to the 'DNA-independent protein kinase' activity," said Igor Nabiev, a principal at the Nano Engineering International Laboratory at the Moscow Institute of Engineering Physics. Fluorescent markers of DNA damage changes."

Fluorescent labels of organic dyes commonly used in microchips are low in sensitivity and unstable. The quantum dot fluorescent semiconductor nanocrystals have unique optical properties, high stability, and a record brightness.

DNA-dependent protein kinase molecules (DNA-PKcs) play a key role in tumor resistance and anti-radiation formation and are an important part of DNA repair mechanisms. It is predicted that the development and screening of DNA-PKcs inhibitors will increase the efficiency of current relevant anti-tumor therapies.

Home Safe

Safety Box,Home Safe,Large Safe Box,Exclusive Safes

Hebei Yingbo Safe Boxes Co.,Ltd , https://www.yingbosafebox.com