According to a recent report by the US Daily Science website, Swedish researchers identified four kinds of neurons in the peripheral auditory system of experimental mice, three of which were newly discovered. They point out that analysis of these cells is expected to lead to new therapies for various hearing impairments. The study was published in the recent issue of Nature Newsletter. When the sound reaches the inner ear, it is converted into an electrical signal that is transmitted to the brain through the nerve cells of the ear in the cochlea. Previously, most of these cells were considered to belong to two types: type 1 and type 2 neurons, with type 1 neurons transmitting most of the auditory information. New research shows that type 1 neurons actually contain three very different cell types. The team used single-cell RNA sequencing to study mice and obtain a catalog of genes expressed in nerve cells, which helps scientists better understand the auditory system and design new therapies and drugs. The researchers also showed that these different types of neurons existed at birth through comparative studies in adult mice. François Lalemende, head of the research department at the Karolinska Institute of Neuroscience, said: "We now know that the central auditory system has three different routes, not one, which makes us It's easier to understand the role of different neurons in the auditory; we also map which genes can be 'shown' in which cells." Lalemend pointed out that the new research has opened the way for the development of new therapies for the treatment of various hearing impairments (such as tinnitus), and the mapping has also helped scientists find ways to influence the function of individual nerve cells in the body. The study suggests that these three neurons may play a role in decoding the intensity of the sound (ie, the volume), a function that is critical for dialogue in noisy environments—depending on the ability to filter out background noise—and this Ability to relate to different forms of hearing impairment, such as tinnitus or hyperesthesia (allergic to sound). Lalemend explained: "Once we know which neurons cause hearing hypersensitivity, we can begin to study new therapies to protect or repair them. The next step is to show how these nerve cells affect the auditory system and help develop Better hearing aids such as cochlear implants, etc." (Reporter Liu Xia) Source: Technology Daily Squid Frozen,Frozen Squid Illex,Fresh Squid,Frozen Pacific Squid Zhoushan City Shuangying Aquatic Products Co., Ltd.  , https://www.shuangying-aquatic.com
Three new neurons in the inner ear of the experimental mouse have helped develop new treatments for hearing impairment.
:2018-09-26