Bird Flu Biology

Bird flu, the full name bird and bird influenza, is an animal-borne disease caused by a virus and usually infects only birds. In rare cases, it can infect pigs. The bird flu virus is highly specific to a particular species, but in rare cases it can spread across species barriers. Since humans were found to have been infected with bird flu in Hong Kong in 1997, the condition has attracted the attention of WHO worldwide. Since then, the disease has sporadically erupted in Asia, but since December 2003, bird flu has exploded in many countries in East Asia, mainly in Vietnam, South Korea, and Thailand, and has caused many Vietnamese patients to die. Until mid-2005, the epidemic did not show signs of subside but it continued to spread. There are also cases as far as many countries in Eastern Europe.

Classification of pathogens

According to the antigenic classification of nuclear proteins, avian influenza virus belongs to influenza A virus. Influenza A virus is divided into several subtypes based on the antigenicity of hemagglutinin and neuraminidase located on its mantle. Hemagglutinin (H) There are 16 subtypes; neuraminidase (N) has 9 subtypes. All of these subtypes can infect birds and highly pathogenic in birds are H5, H7 subtypes. The typical chicken bird flu virus is H7N7, resulting in H5N2 pandemic in the eastern United States in 1983 and 1984. The current human infection in Southeast Asia is H5N1. The H5N1 strain that was discovered in 1997 was identified as the source of influenza at the time. In 1999, there was a human infection with H9N2 avian influenza in Hong Kong. In 2003, the Netherlands had human infection with H7N7 avian influenza; in January 2006, H3N2 occurred in the United States. Based on the toxicity in poultry populations, bird flu can be classified as low pathogenic (LPAI) and highly pathogenic (HPAI). The strains of H5 and H7 subtypes are found in both highly pathogenic and low pathogenic types, and H9 is only found in low pathogenic types. Low-pathogenic avian influenza can cause mild respiratory symptoms in poultry, reduced food intake, decreased egg production and sporadic death. Highly pathogenic avian influenza is the most serious, with high morbidity and mortality, and infected chickens often die.

Bird flu infection

Avian influenza can be transmitted to many kinds of animals, including birds, pigs, horses, seals, whales and humans. However, wild birds act as an asymptomatic carrier and transmit it to more susceptible poultry. There is no evidence that the virus can survive in cooked meat, mainly through the respiratory and fecal-oral routes. The virus first infects the digestive tracts of birds, which replicate in the epithelial cells of the small intestine and eventually spread with the faeces. The symptoms of bird flu in animals are very different, but the type of virulent may be fatal within a few days. Symptoms of bird flu transmission to humans are similar to those of other flu. They include fever, cough, sore throat, muscle aches, conjunctivitis, etc. Severe cases of breathing problems and pneumonia may be life-threatening. There are also some atypical symptoms. In one case, a boy infected with the H5N1 virus developed diarrhea.

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