Brookfield Viscometer in the ointment industry

When a consumer uses a cream, its rheological behavior has a considerable relationship with its physical handling properties. When the patient puts the ointment on the affected area, they are expected to have a thicker viscosity so that they are not prevented from escaping from the application. The high viscosity, which is close to zero shear, is characteristic of this behavior; we can characterize this performance by measuring the yield stress of the ointment (the shear stress that causes the ointment to begin to flow). When designing a cream, it is often necessary to consider whether it is easy to use when rubbed. This is also known as the (paste) shear thinning behavior. Using a Brookfield cone and plate Brookfield Engineering Brookfield Engineering Brookfield viscometer or rheometer, you only need a small amount of sample, you can easily test the yield properties of creams and shear thinning behavior.

For example, fly with Boler Brookfield Brookfield Brookfield viscometer required   The DV-III+CP Programmable Rheometer is equipped with a cone spindleCPE-40 rotor and can be measured from a low shear to a high shear range with a sample volume of 0.5 ml. You can choose Brookfield Brookfield Engineering of TC-501Circulating Water Bath series thermostatic water bath temperature control.

Test Method

As long as a procedural
measure viscosity test method can clearly see the significant difference between the two creams. As can be seen from the graph below, the viscosity test was carried out under conditions where the shear rate was changed from 37 s-1 to 375 s-1 and then from 375 s-1 to 37 s-1. The entire measurement time takes 6.5 minutes. Both ointments exhibited shear thinning characteristics. When sample #1 was lowered from high shear to low shear, its viscosity was significantly lower than the value during the rise of shear rate, and the viscosity loss of sample #2 The degree is not so big. This property of decreasing viscosity as the shear time increases is called thixotropy. These tests can inspire drug manufacturers to achieve the desired performance by changing the formulation of the drug.

Other options

Using a Brookfield Brookfield Engineering Rheocalc® optional software can automatically collect and store test data, and processing the data rheological mathematical model, test parameters can be analyzed, for example, yield stress (shearing stress cream begins to flow) and plastic Viscosity (ie the shear stress function required to maintain constant current). In the case of this article, these experimental data were analyzed using the Bingham fluid model, which is one of several mathematical models on Rheocalc® software.

The American B rookfield DV-S rotary viscometer is used in a wide range of applications. The DV-S rotary viscometer features the following:

1. The stress sensor of the American B rookfield DV-S viscometer is a high-density sensor; the DV-S rotary viscometer has 4 stress sensing points per revolution, and the reaction is fast, while the partial viscometer imitation product only rotates per revolution. A sensing point, at low speeds, the number of sensing points of the viscometer determines the refresh rate of the viscosity measurement data. For example, if the viscometer has only one sensing point under the measurement condition of 1 rpm, It takes 60 seconds for new data to be generated, and the viscometer is simply not practical.

2. The rotor processing precision of the American B rookfield DV-S viscometer reaches a very high level. Therefore, if one of the vibrometers is inadvertently damaged, a new rotor can be purchased without the need to send the entire viscometer. Return to the factory for pairing correction of the rotor-viscometer;

3. In order to meet the needs of the Chinese market, the American B rookfield Bolerfei manufacturer printed the Chinese logo on the DV-S viscometer product. The DV-S rotary viscometer is extremely simple and simple. The manufacturer has prepared Chinese for the DV-S rotary viscometer. Version of the operating instructions and installation materials.

Brookfield Engineering Brookfield viscometer understand, please visit Brookfield Brookfield Engineering Laboratory Standards viscometer exclusive agent East NSC instrument !

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