Pfizer scientists use 3D printing to help improve R&D efficiency

Release date: 2016-05-04

You can't make any mistakes when your product can affect the health of millions of people. As one of the world's largest pharmaceutical companies, Pfizer is committed to producing drugs that consumers can trust. To this end, many of the drugs launched by the company are quite popular, such as Advil, Good Deposit, Lyrica, Zoloft, Celebrex, and Epinephrine (EpiPen). )Wait.

Of course, in order to improve research efficiency, Pfizer's global R&D scientists often use trusted resources and tools to simplify production and get accurate results. That's why they chose the MakerBot 3D printer to help them develop an efficient way to test new orthopedic and rheumatoid arthritis drugs.

The main work of scientists David Zakur and Edwin Berryman is the research and testing of new treatments by Pfizer's Department of Comparative Medicine. Currently they are working on a study for the treatment of arthritis, a disease that affects the bones and cartilage at the joints of the human body.

It is understood. The main work of these two scientists is to check the bones of rats with arthritis after receiving different experimental treatments. The target of the operation is a 1.5 cm long proximal tibia, which is human and mouse. There is a section of bone on the knee that is shaped like a keel on a canoe.

And scientists need to get high-resolution scans of these bones. This sounds simple, but each bone needs to be in the same position for each scan. The shape of the proximal humerus of the mouse is irregular and it is cumbersome to operate. Because of the limited budget, it is impossible for scientists to spend thousands of dollars to buy a fixture to hold these bones, so their work can be cumbersome and hard. Scientists even made a self-contained stent with a conical tube and a pipette. Despite some effects, the self-made stent still had a 40% failure rate.

This situation has changed since the purchase of a MakerBot Replicator 3D printer (fifth generation) in their department. Zakur and Berryman asked their colleague, another Phaeton scientist, Tim Winton, to design and 3D print a bone fixation device that would safely maintain the stability of the rat bones they studied.

“Once the final design is complete, we need to print a large number of mounting brackets. Replicator once again demonstrates its consistent print quality, and the quality of each 3D printed stand is fairly consistent,” Winton shared. The new 3D printing bracket simplifies the entire research process. Thanks to increased efficiency, Zakur and Berryman were able to quickly complete the scan, avoiding outsourcing costs and improving the accuracy of their research.

(Compiled from MakerBot Blog)

Source: Tiangongshe

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