Scientists find that vitamin D supplementation does not prevent heart disease and cancer

Scientists find that vitamin D supplementation does not prevent heart disease and cancer

February 01, 2019 Source: Ministry of Science and Technology

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Researchers in the United States have concluded from a large clinical trial that taking vitamin D supplements does not reduce the risk of a fatal heart attack, stroke, or invasive cancer.

Scientists have long known that people with low levels of vitamin D in their blood have a higher risk of heart disease, stroke, heart failure and atrial fibrillation. However, whether vitamin D supplementation daily can prevent these diseases in people with normal vitamin D levels is not known. So epidemiologists at the Brigham and Women's Hospital in Boston and Harvard Medical School have launched a phase III clinical trial, the largest randomized trial to test whether vitamin levels can prevent cardiovascular disease.

They tracked 25,871 US participants - men aged 50 years and older and women aged 55 and older - for up to 6 years. Participants were relatively healthy and did not have a history of cardiovascular disease or cancer at the outset. The trial also included 5,106 black participants, because pigmentation can reduce the production of vitamin D in the skin, so people with darker skin have lower vitamins.

In this large-scale clinical trial of 2,000 international units or IU of vitamin D per day, 396 of the daily vitamin D supplements suffered from heart disease or stroke, or died of cardiovascular disease; There were 409 patients in the placebo group. Of the people taking vitamin D, 793 were diagnosed with invasive cancer, including breast, prostate, and colorectal cancer, compared with 824 in the placebo group. The difference between the two is minimal.

The researchers published the article in the New England Journal of Medicine on November 10, 2018.

Vitamin D is a sterol derivative with anti-caries effect, also known as anti-caries vitamin. Vitamin D has been hailed as a drug that strengthens bones, prevents obesity, diabetes, heart disease and autoimmune diseases. "This study shows that the general population does not need to take vitamin D to maintain cardiovascular health or cancer health," said Erin Michos, a preventive cardiologist at Johns Hopkins University School of Medicine. "This is by far the most authoritative trial on this subject." University of Oxford epidemiologist Jane Armitage pointed out that the trial is large in scale, diverse in race, balanced between men and women, and adherence to treatment is good. Because of this, “I think we need to accept the good test of this hypothesis that it is not worthwhile to generally supplement the proper dose of vitamin D,”

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