In pharmaceutical sterilization, have you ever experienced sterilization failures such as wet clothes, long media, spore strips, etc. after sterilization? What is the cause of sterilization failure? The following analysis from the biological perspective of steam sterilization principle: a) Time: According to the micro-logging curve of the semi-logarithmic model, it can be known that if the equivalent sterilization time is reduced by 5 minutes, only 4 logs of microorganisms can be killed (the sterility level is to kill 6 log microorganisms) c) Steam contact: At the same temperature, the energy stored in the steam is greater than the dry air and water. Steam sterilization releases energy when it comes into contact with the object. Therefore, the steam must be in full contact with the item to be sterilized. For example, a container for closing the valve, a bottle cap or an empty glass bottle with an aluminum cover attached to the sterilizer. In this way, the steam cannot directly contact the inner surface and cannot be sterilized. d) Air removal: Air is the biggest obstacle to sterilization and must be removed from the chamber. If there is air in the chamber, there will be a cold spot and there will be an area where sterilization is not complete. e) Steam quality: The effect of the quality of the steam on the sterilization rate L in saturated steam sterilization depends on the extent to which the steam mass deviates from the ideal steam state. The energy contained in steam having a dry value of less than 1.0 <pure saturated steam; superheated steam sterilization rate <saturated steam; steam containing non-condensable gas makes steam a mixture, and there is a cold spot. f) Drying: Liquids are ideal pollution conductors in an open atmosphere, so ensuring dry loading is a necessary condition to prevent secondary pollution. As a long-term partner of the German MMM Group in China, Elite can provide customized consulting services for customers' special needs and develop detailed solutions for customers. Each model of sterilizer adjusts temperature, time, pressure and pressure rate of change for different product characteristics. With the development of the extraction and separation of the active ingredients of medicinal plants, the determination of their composition and structure, and the study of their pharmacological effects, some isolated and purified plant extracts have begun to receive attention. Some companies that produce plant extracts are actively researching and developing such new products, and some larger cosmetic companies have also carried out a lot of research work to separate and prepare pure extracts and apply them to various products. These plant extracts have high active ingredients, do not contain or less contain other irrelevant substances, contain one or several relatively pure components, the content and structure of the components are accurate, and there are clear quality standards and inspections. Methods, products have undergone pharmacological tests, clinical trials and activity tests. The use of such plant extracts is more effective and practical, and it is convenient for product preservation and quality control, but the cost is higher than that of general extracts. The following discusses some of the isolated and purified plant extracts that are used in cosmetics and whose components and structures are well understood. Pure natural plant material,Salicin Extract Ingredients Powder, Factory Price Salicin Powder,Phloretin Extract Price, Olibanum Extract Price Xi'an Henrikang Biotech Co.,Ltd , https://www.henrikangbio.com
b) Temperature: As can be seen from the figure, the kill rate of the same number of microorganisms at 118 ° C is half that at 121 ° C. Therefore, at 118 ° C, 2 times the exposure time is required to kill the same amount of microorganisms. 
Due to the influence of traditional Chinese medicine culture, my country's Plant Extract industry has unique development advantages. With abundant resource advantages and technological advantages, China has become one of the most important suppliers of plant extracts in the world.