Release date: 2017-05-05 Scientists have discovered that Parkinson may begin in the intestine before it spreads to the brain. They found that patients who underwent vagus nerve stem surgery had a lower probability of developing Parkinson's disease. The vagus nerve stem cut cuts off the vagus nerve, which connects the intestines and the brain. In a five-year study, patients who had cut off this connection had a 40% lower prevalence than those who did not. Unexpectedly, Parkinson began in the intestines instead of the brain. According to the team led by Bojing Liu of the Karolinska Institute in Sweden, this probability shows a big difference. It also supports the notion that this brain disease is related to certain conditions in our abdomen. If we can better understand the principles of this connection, then we may be better able to stop Parkinson from appearing. Liu said: "These results provide prima facie evidence that Parkinson may begin in the intestine. In addition, people with Parkinson often have gastrointestinal problems such as constipation, and such evidence supports the hypothesis. Before these people suffer from Parkinson's I have been suffering from constipation for many years." The vagus nerve can help control various unconscious problems such as heart rate and digestion, and the vagus nerve trunk surgery works because it can eliminate ulcers when the stomach acid produced in the stomach reaches a dangerous level. For the study, the researchers collected 40 years of data from the Swedish national record, comparing 9,430 people who underwent vagus nerve resection and 377,200 who did not. In the beginning, the two groups had similar rates of Parkinson's, until the researchers began to study people who had undergone vagus nerve resection from a smaller scale. Overall, 19 patients (0.78% of the sample) developed Parkinson's disease more than five years after undergoing complete vagus nerve resection. In contrast, 60 (1.08%) experienced the same situation in people who underwent selective vagotomy. In contrast, in the first five years, 3,932 (1.15%) of those who did not have surgery had Parkinson's. Obviously, the vagus nerve plays a role in this. So what happened in the end? Scientists have come up with the hypothesis that intestinal proteins begin to fold in the wrong way, genetic errors are transmitted between cells, and ultimately affect the brain. As Parkinson's condition worsens, the neurons in the patient's brain are killed, causing the patient to tremble, stiffen and difficult to move. But scientists still have not been able to fully determine the cause of Parkinson's. The latest research can only point them to the direction. Coincidentally, when scientists experimented with mice last year, they found that there was a certain connection between the mixing of specific intestinal bacteria and people suffering from Parkinson. Also, a study in the United States earlier this year distinguished between the intestinal bacteria of Parkinson's patients and the intestinal bacteria of healthy people. All of this helps scientists prevent Parkinson. If we know the cause of Parkinson, then we can block its source. But we should not be too happy too soon, after all, Parkinson is very complicated. Scientists have no way to rule out all the underlying factors, including caffeine and smoking. It is also worth noting that Parkinson's is classified as a syndrome, which suggests that a range of different but related symptoms may also have multiple causes. Liu said: "We need more research to validate this hypothesis to help us better understand the role of the vagus nerve in people suffering from Parkinson's disease." The study has been published in Neurology. Source: Omelette Net Office Safe Box,Commercial Safe Box,Heavy Biometric Office Safe Box,Large Office Safe Box Hebei Yingbo Safe Boxes Co.,Ltd , https://www.yingbosafes.com