Release date: 2017-03-01 China is a big country with liver disease, and the incidence of hepatitis B remains high. Slowly adding acute liver failure is a newly defined end-stage syndrome of liver disease, which is a systemic multiple organ failure caused by acute decompensation based on chronic liver disease. It is a short-term death of all liver diseases. The highest rate. Once the cirrhosis stage progresses to slow plus acute liver failure, the three-month mortality rate is as high as 50-70%. Liver transplantation in the early stages of the disease is currently the only effective treatment for the disease. The latest study found that "capillary bile ductalization of liver cells" can promote liver function regeneration, which is expected to reduce the rate of liver replacement and mortality in patients with end-stage liver disease. The Sino-German Slow and Acute Liver Failure Research Collaboration Team, jointly organized by Renji Hospital affiliated to Shanghai Jiaotong University School of Medicine and Heidelberg University of Germany, analyzed more than 1,000 patients and found that although there are 50 cases of slow and acute liver failure, -70% of high mortality, but 30-50% of patients can survive, and the key factor determining whether the liver can restore function is "capillary bile ductalization of liver cells." Prof. Li Hai, from the Chinese Department of Gastroenterology, Renji Hospital, who participated in the project, said that the liver has a strong compensatory function, so that 20-30% of liver function recovery can make patients survive. The key factor in determining whether the liver can restore function is "capillary bile ductalization of liver cells." The appearance of this structure means that the regenerated hepatocytes can not only function as a synthetic amino acid or a metabolically harmful substance, but also can smoothly discharge harmful substances such as bilirubin and bile acid to the biliary tract. The formation of this structure represents the true function of hepatocytes, the so-called "functional liver regeneration". The researchers found that all subjects with hepatic necrosis developed varying degrees of hepatocyte regeneration in the liver within 2 weeks. However, only 5 surviving subjects truly had functional liver regeneration "capillary bile ducts of hepatocytes", and patients with death and treatment failure were unable to form this important structure. Experts say that "functional liver regeneration" is a key factor in determining the survival of patients with chronic liver failure. The findings of this achievement provide a broad space for the treatment of future diseases. It is not only possible to develop a targeted drug that promotes "capillary bile ductalization of hepatocytes", but also to promote the formation of "capillary bile duct of hepatocytes" by improving the microenvironment of the lesioned liver. Source: Look at the News Science Network Radial Artery Compression Tourniquets Radial Artery Compression Tourniquets,tourniquet oem,medical tourniquets,tourniquet pneumatic Anesthesia Medical Co., Ltd. , https://www.medicaldiverse.com