Artemisia history Artemisia annua has the ancient name "è£" (qìn), which means "to treat malaria." Since ancient times, Chinese herbal medicine practitioners in various parts of China have used several kinds of Artemisia halodendron for medicine. However, from the publication of Li Shizhen's "Compendium of Materia Medica" in 1593 to nearly 400 years of history in 1975, Artemisia apiacea Hance was reputed to be authentic and its position as the "Prince Edward". All other products are fake products (counterfeit drugs). In the history of the Chinese medicine millennium, the famous artemisia annua (also known as Artemisia annua L.) is not even eligible for counterfeit medicine because it has a bitter taste and is difficult to be used as Artemisia annua. Selling money. The people just use it to smoke mosquitoes. In the year 1990, Artemisia annua suddenly came into operation. It changed its status as the "Prince Edward" of Artemisia annua and became famous in the world. To say that Artemisia arborescens "the civet cats change the Prince", it must be traced back to the 20th century. In 1959, the Central Committee of the Communist Party of Vietnam decided to arm and unify Vietnam and dispatched a large number of military personnel to South Vietnam to organize armed subversion. In May 1961, at the request of the government of South Vietnam's Wu Tingjun, President Kennedy sent a special force to South Vietnam, marking the beginning of the Vietnam War. As a socialist country, the former Soviet Union and China will absolutely not stand by and go all out to support the North Vietnamese government. The Vietnam War has gradually escalated and it has become more intense. In the mid-1960s, apart from providing a large amount of material money to support the northern Vietnamese government, the Chinese government dispatched the People's Liberation Army 6886 troops to secretly enter the war. There is no sign of the Chinese People's Liberation Army. The People's Liberation Army soldiers dressed in the yellow-green military uniform of the Vietnamese People's Army, wearing a Ho Chi Minh cap, and are intertwined in the jungles of Vietnam. Soldiers have been infected with malaria, among which the death rate of falciparum malaria is extremely high, which greatly affects combat effectiveness. However, the anti-malarial drug Chloroquine was already resistant to the disease, and medical staffs were unable to understand the large number of combatants. Chairman Mao Zedong and the Central Military Commission are very concerned about this. At the same time, the Vietnamese Communist Army also suffered a significant reduction in malaria, and the Chairman of the Communist Party Central Committee Ho Chi Minh requested the Chinese government to look for alternatives to chloroquine for the treatment of malaria. On May 23, 1967, Mao Zedong ordered a nationwide study to find new drugs that could replace chloroquine in the treatment of malaria. Premier Zhou Enlai participated directly and the State Council established the "5.23" office. Several dozens of national and provincial-level research institutions such as the Institute of Chinese Materia Medica, Institute of Chinese Materia Medica, Institute of Traditional Chinese Medicine, Institute of Traditional Chinese Medicine, Institute of Traditional Chinese Medicine, Ministry of Public Health, and the Yunnan Provincial Institute of Traditional Chinese Medicine undertook this task under the leadership of the “5.23†office under the military regions. The project was relatively secretive and significant scientific research at that time. In the five years from May 1967 to the end of 1972, researchers from all over the world who undertook the 5.23 project turned the bottles and jars left by thousands of Chinese ancestors over thousands of years and tested numerous prescriptions for the treatment of malaria with Chinese herbal medicine. , unilateral, prescription, secret prescription. The yuan, which was calculated in hundreds of millions of yuan, has been spent on a large amount of manpower and material resources. The result was nothing. If it weren't an accidental event, it is not known how to comment on it today. The grand scene of the "5.23" project was a glimpse of the situation. "According to the unified arrangement of the national "May 23" project leading group, Yunnan Province established the "Kunming May 23rd Leading Group" in 1971. The Kunming Military Region logistics and health department, the provincial health department, the provincial science committee and other units are members. There are more than 30 scientific research institutions participating in the troops and localities, and about 320 people directly involved in the research work. There are more than 30 counties and more than 1,400 production teams in 16 prefectures in the province, collecting private anti-malaria herbal medicine unilaterally. There are more than 4,300 prescriptions; in other provinces, there are 6 major units involved in the development and 39 major cooperative units. A nation-wide collaboration and group-military "anti-malaria" battles have begun without a word." "Based on a large number of inspections of the "Materia Medica" record and other medical books and data, scientific researchers from Keban actively collected methods for treating "pendulum" unilaterally, prescription, mosquito repellent, and mosquito control from ethnic groups and nongovernmental doctors. After the collection, experiment and research, the attention was gradually focused on the Chinese medicine “Chang Shan†and the Ma Da Ke plants “Jin Bu Huan†and “Guan Lan Xiangâ€. Although these drugs have obvious antimalarial effects, they unfortunately have incompetence. Overcome toxicity." Car to the mountain without doubt, Liu Minghua Ming Village. The occurrence of an accidental event rewritten the history of Chinese medicine Artemisia annua. At the end of 1972, Fu Liangshu, director of Yunnan 5.23 Leading Group Office, and deputy directors Zhou Jianbo and Li Shu returned from Beijing to participate in the Full Country “5.23†meeting. When communicating to scientific researchers, the Institute of Traditional Chinese Medicine of Beijing Research Institute of Traditional Chinese Medicine discovered Artemisia annua L. Crude extracts have marginal antimalarial effects, but the prospects are not promising. Research has stopped and it is recommended that they screen local Artemisia plants for research. "In the 1973 New Year, Luo Zeyuan went to play at a friend's house at Yunnan University and discovered a lot of wormwood on the Yunda campus." "I took the idea of ​​trying it and picked up a big one to hold it back to the Pharmaceutical Research Institute. After that, she prepared extracts from different solvents of Artemisia selengensis and successfully separated several crystalline ingredients. When engaged in antimalarial drugs for many years, When Huang Quan, who was working on the screening work, saw the result of the screening of the compound numbered Crystalline III, he was surprised to find that all the Plasmodium had disappeared from the mouse blood that had originally been infected with a "starry sky." It was not only an accident.†Huang Heng calmly reminded himself of his surprise. However, after repeated test results, he was excited. “This is not accidental. We have really found effective antimalarial ingredients. Huang Heng told the other members of the group about the unexpected happiness. For a time, everyone was thrilled. After years of hard work, they finally saw a glimmer of hope. “After further research on pharmacodynamics and pharmacology, by the end of March, the team members demonstrated that the bitter crystallization of Artemisia annua indeed has the characteristics of high efficiency and low toxicity against mouse malaria. At the same time, Luo Kaijun will be The plant specimens were sent to the famous classification expert Professor Wu Zhengxuan for identification, named as Artemisia annua L., and therefore, they named the crystal as artemisinin. “Qi Yufang told everyone that Sichuan's Artemisia is Artemisia annua, and its flowering period Late in Yunnan, maybe there will be Sichuan. Without delay, Qi Yufang and Zhan Eryi immediately sent a line to rush to Chongqing. It was learned that Chongqing Pharmaceutical Company was preparing to deal with a batch of unqualified herbal medicines. Overjoyed, they bought 500 kilograms at a time and went back to the factory for processing and extraction. They found that many of the effective ingredients in this series of wormwood can be extracted from them. †The discovery of chrysanthemum artemisinin lays a solid foundation for the civet cats to change the prince for a few years.
Kojic acid is an organic compound with molecular formula of c6h6o4 and molecular weight of 142.11. Colorless prismatic crystal. It is used as Antioxidant and anti radiation agent. It is used in the field of cosmetics. In human skin, tyrosine is catalysed by tyrosinase, and then oxidized and polymerized with oxygen free radical to synthesize melanin. Kojic acid can inhibit tyrosinase synthesis, so it can strongly inhibit the formation of skin melanin, and is safe and non-toxic, and does not produce leukoplakia sequela. Kojic acid has been incorporated into make-up water, facial mask, emulsion and skin cream. It can be used to treat freckles, senile plaques, pigmentation, acne and other high-grade whitening cosmetics effectively.
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Specification: 99%
CAS: 79725-98-7
MOLECULAR FORMULA: C38O6H66
Kojic acid dipalmitate is a derivative of Kojic Acid and palmitic acid, which not only overcomes the instability to light, heat and metallic ion, but keeps the inhibitory tyrosinase activity and prevents the forming of melanin. It is easier to be absorbed by the skin. IMAHERB BIOTECH is one of the professional and credible top quality GMP Manufacture ISO Certified Kojic Acid Dipalmitate Cosmetic Raw Material 99% for sale manufacturers, who is dedicated to produce the top quality organic products which is of great benefits to customers. If you want to know how to buy such products, welcome to contact us and we will offer you the best price.
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Alpha Arbutin, Cosmetic Grade Product, is mainly extracted from the leaves of bearberry. α- Arbutin can also be found in some fruits and other plants. It has the effect of brightening the skin. It can be used in high-grade cosmetics, such as skin care cream, freckle cream, high-grade pearl cream, etc. it can not only make skin care, but also reduce inflammation and anti irritation. Ellagic acid, it has many bioactive functions, such as antioxidant, anticancer, antimutagenic and anti HIV. In addition, ellagic acid is also an effective coagulant, which has a good inhibitory effect on a variety of bacteria and viruses. It can protect the wound from the invasion of bacteria, prevent infection and inhibit ulcer. At the same time, ellagic acid also has antihypertensive and sedative effects. Glycyrrhizic acid, an organic compound, can be used as Sweetener, flavoring agent and flavor enhancer. Using in skin care products can enhance the efficacy of other active substances in sunscreen, whitening, antipruritic, conditioning and scar healing. Sepiwhite Msh Powder is a kind of melanin stimulating hormone( α- MSH receptor antagonist, mainly used in cosmetics as a whitening agent.
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Skin care, sun care, skin whitening/lightening, treatment for pigmentary disorders such as age spots etc.Function:Kojic dipalmitate owns stable chemical property. It will not turn yellow for oxidation, metallic ion, illumination and heating. As fat soluble skin whitening agent,it is easier to be absorbed by skin.With the most advanced technology, kojic dipalmitate synthesized by our company has the most shallow color and the minimum impurity.
