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Roche Reveals Tamiflu Formula: Octagon + Explosive
On the 9th, Switzerland's Roche Pharmaceutical Company briefed the outside world on the ingredients and production technology of the anti-avian flu drug Tamiflu. Surprisingly, the "Tamiflu" component contained an explosive substance, a Chinese seasoning, and a harmless E. coli. "Duffy" has a total of 12 production processes, the initial extraction of shikimic acid from star anise. Since 30 kg of star anise can only process 1 kg of shikimic acid, and star anise grows in only 4 provinces in China, usually harvested in March and May, Roche will not be able to obtain enough if the harvest is poor or the price is too high. raw material. Roche developed a method for producing shikimic acid without using star anise, and it cooperated with a German biotechnology center last year. This new process forces the bacteria to release shikimic acid by overdosing glucose into a harmless E. coli. Currently, two-thirds of Roche's shikimic acid is from star anise and the remaining third is provided by E. coli. After three steps of reactor, filter and dryer, shikimic acid is transformed into an intermediate chemical epoxide. Subsequently, the structure of the epoxide must be opened and converted to another intermediate chemical azide by atom conversion. This process requires the use of highly explosive sodium azide. Next, the azide is made into an active ingredient, which is then mixed with other additives, and finally dried in vacuum to make "Daffy" particles. Many people mistakenly believe that eating more star anise in their daily diet can also prevent bird flu, and even there is a wave of panic buying. Experts therefore warned that direct use of star anise can not prevent bird flu. In general, star anise has a low chance of producing shikimic acid in the cooking process. Star aniseine is contained in the star anise. Excessive consumption may cause poisoning.