The pharmacological effects of Cimicifuga

Pharmacological effects

【Functions】Clearing heat, detoxifying and translucent

【Indications】 poor measles, fever, hot spots, tongue sores, sore throat, sores, erysipelas, no gas in the trap, Jiuxie anus, uterine prolapse, blood clotting.

[3] 1. Pea spicules (like peas, with white pulp, spread from the head and body, not life-threatening). With honey, fried cohosh, ready to eat. Another boiled cohosh, cotton stains sore sauce.

2, sudden swollen poisonous. Cohosh vinegar, coated at any time.

3, throat. The use of Cimicifuga tablets containing pharynx, or Cimicifuga two water Jianshui clothes, cited as a result of vomiting.

4, stomach hot toothache. Cimicifolius decoction, simmer and swallow. Fang added rehmannia can also be.

5, mouth sores. With 50 grams of Cimicifuga, 1.5 grams of Coptis, a total of research for the end. Cotton wrapped Yaomo contains pharynx.

6, hot itch itch. Use Citrus decoction to serve and wash the dumplings.

7, postpartum bad blood. With 150 grams of Cimicifuga, add five liters of sake and boil it for two liters and take it in two doses.

8, solution spasm, Kudzu and other poisons. Use Cimicifuga sauce and serve more.

9. It is used for hot-spotted macules, floating odor of gums, mouth sores, sore throat, and sores. The product is detoxified to cure stomach phlegm floating gums, tongue sores and sore throat, clinical often with gypsum, berberine and other compatibility; fever, fever, body rash and sore swelling, Cimicifuga Can be equipped with silver, forsythia, red peony, angelica equivalent.

1. Effect on the cardiovascular system Cimicifuga water extract injection in animals has the effect of reducing blood pressure, inhibiting myocardium, and slowing heart rate. Xing'an Cimiceng can lower blood pressure and strengthen the heartbeat amplitude without affecting its rhythm.

2. Antibacterial effect in the test tube Cimicifolia can inhibit the growth of Mycobacterium tuberculosis. Its variant Cimicifuga foetida L. var. simplex Huth. Infusing agent (1:4) in test tubes against Xanthomonas mutans, Bacillus sphaericus, Pseudomonas rustiana, red epidermis Fungal bacteria and other skin fungi have different degrees of inhibition. Some reports indicate that Cimicifuga has a strong inhibitory effect on Staphylococcus aureus and Bacillus anthracis; it also has different degrees of inhibitory effect on Streptococcus, Diphtheria, Salmonella, Salmonella typhi, Escherichia coli, and Shigella.

3. Sedative, anticonvulsant effects The water extract of Cimicifuga has a sedative effect, and it can fight convulsions caused by camphor or strychnine in mice experiments. Xing'an Cimicifuga also has a sedative effect on the animal's central nervous system. It contains isoferulic acid that can slow down animals, tend to be sedated, and has relatively weaker toxicity.

4. Effect of antipyretic and cooling effect Xing'an Cimicifuga extract or isoferulic acid can reduce normal body temperature in rats, and have significant antipyretic effect on febrile rats induced by typhoid fever and paratyphoid mixed vaccine. Cimicifuga extracts and Cimicifolia have a cooling effect on experimental animals.

5. The effect on smooth muscle Cimicifuga water extract can inhibit the isolated intestine and pregnancy uterus, on the bladder and non-pregnant uterus excited; Xing'an cosomnia relaxation intestinal smooth muscle; but also enhance the secretion of bronchial and digestive tract glands; The uterus contracts. It has also been reported that the furanchromone derivative Khellin has a clear antispasmodic effect on smooth muscle (bladder, uterus, etc.), and furanochromones are the main active components of the rhizoma of the coccidia.

6. Other effects of methanol extract of Cimicifuga can effectively prevent carbon tetrachloride-induced animal liver injury.

Cimicifuga can significantly shorten the bleeding time before and after frying the charcoal, and can also shorten the clotting time to a certain extent, and have obvious hemostatic effect. Experiments show that: Cimicifuga extract 0.2g (crude drug) / ml, in vitro can significantly prolong bovine thrombin agglutination of human fibrinogen time, there is a strong anticoagulant effect.

Reports have pointed out that wild ephedra has sexual hormone-like effects that can establish adolescent rats with adolescent hypoplasia and climacteric female rats, and also increase ovarian weight and increase the number of corpus luteum in juvenile female rats. Long-term injection of wild cohosh extract to female animals can increase the weight of the uterus.

Drug (poison) science

After people apply large doses, headaches, tremors, tetanic contractions of the limbs, abnormal erection of the penis; no special pharmacological effects of ricinine, can cause skin congestion, and even the formation of ulcers; oral administration causes gastroenteritis, severe dyspnea can occur, Oh, wait. Gastric gavage in mice and intragastric administration of rats were 8.1 g/kg and 7.9 g/kg, respectively.


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